- Mountain lions
- The mule deer is the primary prey of the mountain lion across the West — no predator shapes the species more. Lions take deer of every age, and predation is a leading cause of death from fawn to old buck.
- Hard winters
- Winter is the great filter. Deep snow and sparse, buried forage draw down fat reserves, and fawns and old deer are the first to die when a long winter outlasts their stored energy on limited winter range.
- Worn teeth
- As with all deer, a lifetime of grinding gritty forage wears the molars down. When an old deer can no longer process feed efficiently, it loses condition — old age, in practical terms, arrives through the teeth.
- The rut (bucks)
- Bucks chase, spar, and barely feed through the November rut, entering winter run-down year after year. That annual toll, plus higher hunting pressure on antlered deer, is why bucks average shorter lives than does.
- Disease + hunting
- Mule deer are highly susceptible to chronic wasting disease (CWD), a slow, fatal condition that's a real management concern across much of Colorado. Regulated hunting also factors in, and is one of the tools used to keep herds in balance with their winter range.